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Topological N-glycosylation and site-specific N-glycan sulfation of influenza proteins in the highly expressed H1N1 candidate vaccines

The outbreak of a pandemic influenza H1N1 in 2009 required the rapid generation of high-yielding vaccines against the A/California/7/2009 virus, which were achieved by either addition or deletion of a glycosylation site in the influenza proteins hemagglutinin and neuraminidase. In this report, we ha...

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Publicado en:Sci Rep
Main Authors: She, Yi-Min, Farnsworth, Aaron, Li, Xuguang, Cyr, Terry D.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579265/
https://ncbi.nlm.nih.gov/pubmed/28860626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10714-2
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