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Small molecule-based lineage switch of human adipose-derived stem cells into neural stem cells and functional GABAergic neurons

Cellular reprogramming using small molecules (SMs) without genetic modification provides a promising strategy for generating target cells for cell-based therapy. Human adipose-derived stem cells (hADSCs) are a desirable cell source for clinical application due to their self-renewal capacity, easy ob...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Jihye, Lee, Nayeon, Lee, Jaekwang, Choe, Eun Kyung, Kim, Min Kyung, Lee, Jeonghoon, Byun, Min Soo, Chon, Myong-Wuk, Kim, Seong Who, Lee, C. Justin, Kim, Ju Han, Kwon, Jun Soo, Chang, Mi-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579051/
https://ncbi.nlm.nih.gov/pubmed/28860504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10394-y
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