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The BDNF Val66Met Variant Affects Gene Expression through miR-146b

Variation in gene expression is an important mechanism underlying susceptibility to complex disease and traits. Single nucleotide polymorphisms (SNPs) account for a substantial portion of the total detected genetic variation in gene expression but how exactly variants acting in trans modulate gene e...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Hsu, Pei-Ken, Xu, Bin, Mukai, Jun, Karayiorgou, Maria, Gogos, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579022/
https://ncbi.nlm.nih.gov/pubmed/25771167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.03.004
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