Indirect immobilized Jagged1 suppresses cell cycle progression and induces odonto/osteogenic differentiation in human dental pulp cells

Notch signaling regulates diverse biological processes in dental pulp tissue. The present study investigated the response of human dental pulp cells (hDPs) to the indirect immobilized Notch ligand Jagged1 in vitro. The indirect immobilized Jagged1 effectively activated Notch signaling in hDPs as con...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Manokawinchoke, Jeeranan, Nattasit, Praphawi, Thongngam, Tanutchaporn, Pavasant, Prasit, Tompkins, Kevin A., Egusa, Hiroshi, Osathanon, Thanaphum
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578993/
https://ncbi.nlm.nih.gov/pubmed/28860516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10638-x
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