Long-term PGC1β overexpression leads to apoptosis, autophagy and muscle wasting

Skeletal muscle wasting is prevalent in many chronic diseases, necessitating inquiries into molecular regulation of muscle mass. Nuclear receptor co-activator peroxisome proliferator-activated receptor co-activator 1 alpha (PGC1α) and its splice variant PGC1α4 increase skeletal muscle mass. However,...

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Pubblicato in:Sci Rep
Autori principali: Sopariwala, Danesh H., Yadav, Vikas, Badin, Pierre-Marie, Likhite, Neah, Sheth, Megha, Lorca, Sabina, Vila, Isabelle K., Kim, Eun Ran, Tong, Qingchun, Song, Min Sup, Rodney, George G., Narkar, Vihang A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578977/
https://ncbi.nlm.nih.gov/pubmed/28860475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10238-9
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