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Epigenetic Regulation of PLIN1 in Obese Women and its Relation to Lipolysis

Increased adipocyte lipolysis links obesity to insulin resistance. The lipid droplet coating-protein Perilipin participates in regulation of lipolysis and is implicated in obesity. In the present study we investigate epigenetic regulation of the PLIN1 gene by correlating PLIN1 CpG methylation to gen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bialesova, Lucia, Kulyté, Agné, Petrus, Paul, Sinha, Indranil, Laurencikiene, Jurga, Zhao, Chunyan, Wright, Karin Dahlman, Arner, Peter, Dahlman, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578955/
https://ncbi.nlm.nih.gov/pubmed/28860604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09232-y
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