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Searching for the Pareto frontier in multi-objective protein design
The goal of protein engineering and design is to identify sequences that adopt three-dimensional structures of desired function. Often, this is treated as a single-objective optimization problem, identifying the sequence–structure solution with the lowest computed free energy of folding. However, ma...
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Publicado no: | Biophys Rev |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Berlin Heidelberg
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578931/ https://ncbi.nlm.nih.gov/pubmed/28799089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-017-0288-0 |
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