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Searching for the Pareto frontier in multi-objective protein design

The goal of protein engineering and design is to identify sequences that adopt three-dimensional structures of desired function. Often, this is treated as a single-objective optimization problem, identifying the sequence–structure solution with the lowest computed free energy of folding. However, ma...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biophys Rev
Päätekijät: Nanda, Vikas, Belure, Sandeep V., Shir, Ofer M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578931/
https://ncbi.nlm.nih.gov/pubmed/28799089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-017-0288-0
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