Caricamento...

GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia

An enhancer with amalgamated E-box and GATA motifs (+9.5) controls expression of the regulator of hematopoiesis GATA-2. While similar GATA-2-occupied elements are common in the genome, occupancy does not predict function, and GATA-2-dependent genetic networks are incompletely defined. A “+9.5-like”...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Dev Cell
Autori principali: Hewitt, Kyle J., Katsumura, Koichi R., Matson, Daniel R., Devadas, Prithvia, Tanimura, Nobuyuki, Hebert, Alexander S., Coon, Joshua J., Kim, Jin-Soo, Dewey, Colin N., Keles, Sunduz, Hao, Siyang, Paulson, Robert F., Bresnick, Emery H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578808/
https://ncbi.nlm.nih.gov/pubmed/28787589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.07.009
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !