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Principles of cellular resource allocation revealed by condition-dependent proteome profiling

Growing cells coordinate protein translation with metabolic rates. Central to this coordination is ribosome production. Ribosomes drive cell growth, but translation of ribosomal proteins competes with production of non-ribosomal proteins. Theory shows that cell growth is maximized when all expressed...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Metzl-Raz, Eyal, Kafri, Moshe, Yaakov, Gilad, Soifer, Ilya, Gurvich, Yonat, Barkai, Naama
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578734/
https://ncbi.nlm.nih.gov/pubmed/28857745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28034
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