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Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock

Type 1 Serine/Threonine Kinase Receptors (STKR1) transduce a wide spectrum of biological signals mediated by TGF-β superfamily members. The STKR1 activity is tightly controlled by their regulatory glycine-serine rich (GS) domain adjacent to the kinase domain. Despite decades of studies, it remains u...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Comput Biol
मुख्य लेखकों: Botello-Smith, Wesley M., Alsamarah, Abdelaziz, Chatterjee, Payal, Xie, Chen, Lacroix, Jerome J., Hao, Jijun, Luo, Yun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578689/
https://ncbi.nlm.nih.gov/pubmed/28827795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005711
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