Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis

OBJECTIVES: Epidemiological and experimental studies have established obesity to be an important risk factor for osteoarthritis (OA), however, the mechanisms underlying this link remains largely unknown. Here, we studied local inflammatory responses in metabolic-OA. METHODS: Wistar rats were fed wit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Antonia RuJia, Panchal, Sunil K., Friis, Thor, Sekar, Sunderajhan, Crawford, Ross, Brown, Lindsay, Xiao, Yin, Prasadam, Indira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578643/
https://ncbi.nlm.nih.gov/pubmed/28859108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183693
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