Studies on the adaptation of influenza viruses to MDCK cells.

The amino acid sequences and biological properties of the haemagglutinin of three variants of the influenza virus X-31 (H3N2) selected for their capacity to grow in MDCK cells are reported. In two variants, amino acid substitutions at HA1 residues 8 and 144 correlated with the loss of a site for gly...

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Bibliographic Details
Main Authors: Rott, R, Orlich, M, Klenk, H D, Wang, M L, Skehel, J J, Wiley, D C
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC557858/
https://ncbi.nlm.nih.gov/pubmed/6526017
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