Local inner ear application of dexamethasone in cochlear implant models is safe for auditory neurons and increases the neuroprotective effect of chronic electrical stimulation

Dexamethasone (DEX) can reduce fibrous tissue growth as well as loss of residual hearing which may occur after cochlear implantation. Little is known about the effect of local inner ear DEX treatment on the spiral ganglion neurons (SGN), which are the target of the electrical stimulation with a coch...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Scheper, Verena, Hessler, Roland, Hütten, Mareike, Wilk, Maciej, Jolly, Claude, Lenarz, Thomas, Paasche, Gerrit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578571/
https://ncbi.nlm.nih.gov/pubmed/28859106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183820
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