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Translesion synthesis by yeast DNA polymerase ζ from templates containing lesions of ultraviolet radiation and acetylaminofluorene

In the yeast Saccharomyces cerevisiae, DNA polymerase ζ (Polζ) is required in a major lesion bypass pathway. To help understand the role of Polζ in lesion bypass, we have performed in vitro biochemical analyses of this polymerase in response to several DNA lesions. Purified yeast Polζ performed limi...

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Detalhes bibliográficos
Main Authors: Guo, Dongyu, Wu, Xiaohua, Rajpal, Deepak K., Taylor, John-Stephen, Wang, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55783/
https://ncbi.nlm.nih.gov/pubmed/11433034
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