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Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma
Clear cell renal cell carcinoma (ccRCC), the most common form of Kidney cancer, is characterized by frequent mutations of the von Hippel-Lindau (VHL) tumor suppressor gene in ~85% of sporadic cases. Loss of pVHL function affects multiple cellular processes, among which the activation of hypoxia indu...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578163/ https://ncbi.nlm.nih.gov/pubmed/28812986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081774 |
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