Tumor-Stroma Crosstalk in Bone Tissue: The Osteoclastogenic Potential of a Breast Cancer Cell Line in a Co-Culture System and the Role of EGFR Inhibition

Although bone metastases represent a major challenge in the natural history of breast cancer (BC), the complex interactions involved have hindered the development of robust in vitro models. The aim of this work is the development of a preclinical model of cancer and bone stromal cells to mimic the b...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Mercatali, Laura, La Manna, Federico, Miserocchi, Giacomo, Liverani, Chiara, De Vita, Alessandro, Spadazzi, Chiara, Bongiovanni, Alberto, Recine, Federica, Amadori, Dino, Ghetti, Martina, Ibrahim, Toni
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578045/
https://ncbi.nlm.nih.gov/pubmed/28758931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081655
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