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Clinical Role of ASCT2 (SLC1A5) in KRAS-Mutated Colorectal Cancer

Mutation in the KRAS gene induces prominent metabolic changes. We have recently reported that KRAS mutations in colorectal cancer (CRC) cause alterations in amino acid metabolism. However, it remains to be investigated which amino acid transporter can be regulated by mutated KRAS in CRC. Here, we pe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Toda, Kosuke, Nishikawa, Gen, Iwamoto, Masayoshi, Itatani, Yoshiro, Takahashi, Ryo, Sakai, Yoshiharu, Kawada, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578022/
https://ncbi.nlm.nih.gov/pubmed/28749408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081632
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