Reprimo, a Potential p53-Dependent Tumor Suppressor Gene, Is Frequently Hypermethylated in Estrogen Receptor α-Positive Breast Cancer

Aberrant DNA methylation is a hallmark of many cancers. Currently, there are four intrinsic molecular subtypes in breast cancer (BC): Luminal A, B, Her2-positive, and triple negative (TNBC). Recently, The Cancer Genome Atlas (TCGA) project has revealed that Luminal subtypes have higher levels of gen...

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Pubblicato in:Int J Mol Sci
Autori principali: Buchegger, Kurt, Riquelme, Ismael, Viscarra, Tamara, Ili, Carmen, Brebi, Priscilla, Huang, Tim Hui-Ming, Roa, Juan Carlos
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577992/
https://ncbi.nlm.nih.gov/pubmed/28809778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081525
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