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Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy
Haploinsufficiency of the melanocortin-4 receptor, the most common monogenetic obesity syndrome in humans, is associated with a reduction in autonomic tone, bradycardia, and incidence of obesity-associated hypertension. Thus, it has been assumed that melanocortin obesity syndrome may be protective w...
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| Publicado en: | eLife |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577919/ https://ncbi.nlm.nih.gov/pubmed/28829041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28118 |
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