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TP53 Overexpression is an Independent Adverse Prognostic Factor in de novo Myelodysplastic Syndromes with Fibrosis

Bone marrow (BM) fibrosis is associated with poor prognosis in patients with de novo myelodysplastic syndromes (MDS). TP53 mutations and TP53 (p53) overexpression in MDS are also associated with poor patient outcomes. The prevalence and significance of TP53 mutations and TP53 overexpression in MDS w...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Loghavi, Sanam, Al-Ibraheemi, Alyaa, Zuo, Zhuang, Garcia-Manero, Guillermo, Yabe, Mariko, Wang, Sa A., Kantarjian, Hagop M., Yin, C. Cameron, Miranda, Roberto N., Luthra, Raja, Medeiros, L. Jeffrey, Bueso-Ramos, Carlos E., Khoury, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577911/
https://ncbi.nlm.nih.gov/pubmed/26123119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13529
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