Exosomes isolated from cancer patients’ sera transfer malignant traits and confer the same phenotype of primary tumors to oncosuppressor-mutated cells

BACKGROUND: Horizontal transfer of malignant traits from the primary tumor to distant organs, through blood circulating factors, has recently become a thoroughly studied metastatic pathway to explain cancer dissemination. Recently, we reported that oncosuppressor gene-mutated human cells undergo mal...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Abdouh, Mohamed, Hamam, Dana, Gao, Zu-Hua, Arena, Vincenzo, Arena, Manuel, Arena, Goffredo Orazio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577828/
https://ncbi.nlm.nih.gov/pubmed/28854931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0587-0
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