Comprehensive genomic profiling in routine clinical practice leads to a low rate of benefit from genotype-directed therapy

BACKGROUND: Describe a single-center real-world experience with comprehensive genomic profiling (CGP) to identify genotype directed therapy (GDT) options for patients with malignancies refractory to standard treatment options. METHODS: Patients who had CGP by a CLIA-certified laboratory between Nove...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Hilal, Talal, Nakazawa, Mary, Hodskins, Jacob, Villano, John L., Mathew, Aju, Goel, Guarav, Wagner, Lars, Arnold, Susanne M., DeSimone, Philip, Anthony, Lowell B., Hosein, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577820/
https://ncbi.nlm.nih.gov/pubmed/28854908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3587-8
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