Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice

OBJECTIVE: Aortic vascular stiffness has been implicated in the development of cardiovascular disease (CVD) and chronic kidney disease (CKD) in obese individuals. However, the mechanism promoting these adverse effects are unclear. In this context, promotion of obesity through consumption of a wester...

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Bibliografiske detaljer
Udgivet i:Metabolism
Main Authors: Aroor, Annayya R., Jia, Guanghong, Habibi, Javad, Sun, Zhe, Ramirez-Perez, Francisco I., Brady, Barron, Chen, Dongqing, Martinez-Lemus, Luis A., Manrique, Camila, Nistala, Ravi, Whaley-Connell, Adam T., Demarco, Vincent, Meininger, Gerald A., Sowers, James R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577816/
https://ncbi.nlm.nih.gov/pubmed/28764846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2017.06.006
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