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Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome

BACKGROUND: Aberrant CpG island methylation has been increasingly recognized as a common event in myelodysplastic syndrome (MDS). To date, most of the previous studies of miR-124 in MDS have focused on epigenetic changes and little is known about the underlying mechanism through which miR-124 regula...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Wang, Hong, Zhang, Tong-Tong, Jin, Song, Liu, Hong, Zhang, Xiang, Ruan, Chang-Geng, Wu, De-Pei, Han, Yue, Wang, Xiao-Qin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577794/
https://ncbi.nlm.nih.gov/pubmed/28861128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0388-5
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