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The Middle Fragment of Helicobacter pylori CagA Induces Actin Rearrangement and Triggers Its Own Uptake into Gastric Epithelial Cells

Cytotoxin-associated gene product A (CagA) is a major virulence factor secreted by Helicobacter pylori. CagA activity in the gastric epithelium is associated with higher risk of gastric cancer development. Bacterial type IV secretion system (T4SS)-mediated translocation of CagA into the cytosol of h...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Tohidpour, Abolghasem, Gorrell, Rebecca J., Roujeinikova, Anna, Kwok, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577571/
https://ncbi.nlm.nih.gov/pubmed/28788072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9080237
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