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T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer’s Disease

BACKGROUND: T3D-959, a dual PPAR-δ/PPAR γ nuclear receptor agonist and former diabetes drug candidate, has been repositioned as an Alzheimer’s disease (AD)-modifying therapy. OBJECTIVE: This study examines the effectiveness and mechanisms of T3D-959’s therapeutic effects using in vivo and ex vivo ra...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Tong, Ming, Deochand, Chetram, Didsbury, John, de la Monte, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577391/
https://ncbi.nlm.nih.gov/pubmed/26836193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-151013
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