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A Scalable Platform to Identify Fungal Secondary Metabolites and Their Gene Clusters
The genomes of filamentous fungi contain up to ~90 biosynthetic gene clusters (BGCs), encoding diverse secondary metabolites, an enormous reservoir of untapped chemical potential. However, recalcitrant genetics, cryptic expression, and unculturability prevent the systematic exploitation of these gen...
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| Publicado no: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577364/ https://ncbi.nlm.nih.gov/pubmed/28604695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2408 |
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