MHC matching improves engraftment of iPSC-derived neurons in non-human primates

The banking of human leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells (iPSCs) is considered a future clinical strategy for HLA-matched cell transplantation to reduce immunological graft rejection. Here we show the efficacy of major histocompatibility complex (MHC)-matched allogeneic...

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Publié dans:Nat Commun
Auteurs principaux: Morizane, Asuka, Kikuchi, Tetsuhiro, Hayashi, Takuya, Mizuma, Hiroshi, Takara, Sayuki, Doi, Hisashi, Mawatari, Aya, Glasser, Matthew F., Shiina, Takashi, Ishigaki, Hirohito, Itoh, Yasushi, Okita, Keisuke, Yamasaki, Emi, Doi, Daisuke, Onoe, Hirotaka, Ogasawara, Kazumasa, Yamanaka, Shinya, Takahashi, Jun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577234/
https://ncbi.nlm.nih.gov/pubmed/28855509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00926-5
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