Variable repeats in the eukaryotic polyubiquitin gene ubi4 modulate proteostasis and stress survival

Ubiquitin conjugation signals for selective protein degradation by the proteasome. In eukaryotes, ubiquitin is encoded both as a monomeric ubiquitin unit fused to a ribosomal gene and as multiple ubiquitin units in tandem. The polyubiquitin gene is a unique, highly conserved open reading frame compo...

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Pubblicato in:Nat Commun
Autori principali: Gemayel, Rita, Yang, Yudi, Dzialo, Maria C., Kominek, Jacek, Vowinckel, Jakob, Saels, Veerle, Van Huffel, Leen, van der Zande, Elisa, Ralser, Markus, Steensels, Jan, Voordeckers, Karin, Verstrepen, Kevin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577197/
https://ncbi.nlm.nih.gov/pubmed/28855501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00533-4
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