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Functional analysis of a novel, thyroglobulin-embedded microRNA gene deregulated in papillary thyroid carcinoma

MicroRNAs, non-coding regulators of gene expression, are known culprits of thyroid cancer. Using next-generation sequencing, we identified a novel microRNA gene, encoded within an important thyroid regulator – thyroglobulin, and analyzed its functionality in the thyroid gland. In vitro and in silico...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kolanowska, Monika, Wójcicka, Anna, Kubiak, Anna, Świerniak, Michał, Kotlarek, Marta, Maciąg, Monika, Gaj, Paweł, Koperski, Łukasz, Górnicka, Barbara, Jażdżewski, Krystian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577171/
https://ncbi.nlm.nih.gov/pubmed/28855631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10318-w
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