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Nanocurcumin is superior to native curcumin in preventing degenerative changes in Experimental Cerebral Malaria

Curcumin has many pharmacological activities despite its poor bioavailability and in vivo stability. Here, we show that a nanoformulated curcumin (PLGA-curcumin) has better therapeutic index than native curcumin in preventing the onset of neurological symptoms and delaying the death of mice in exper...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Dende, Chaitanya, Meena, Jairam, Nagarajan, Perumal, Nagaraj, Viswanathan Arun, Panda, Amulya Kumar, Padmanaban, Govindarajan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577147/
https://ncbi.nlm.nih.gov/pubmed/28855623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10672-9
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