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DNA damage regulates direct association of TOR kinase with the RNA polymerase II–transcribed HMO1 gene
The mechanistic target of rapamycin complex 1 (mTORC1) senses nutrient sufficiency and cellular stress. When mTORC1 is inhibited, protein synthesis is reduced in an intricate process that includes a concerted down-regulation of genes encoding rRNA and ribosomal proteins. The Saccharomyces cerevisiae...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576907/ https://ncbi.nlm.nih.gov/pubmed/28701348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0024 |
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