Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice

Pancreatitis is a debilitating disease of the exocrine pancreas that, under chronic conditions, is a major susceptibility factor for pancreatic ductal adenocarcinoma (PDAC). Although down-regulation of genes that promote the mature acinar cell fate is required to reduce injury associated with pancre...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Fazio, Elena N., Young, Claire C., Toma, Jelena, Levy, Michael, Berger, Kurt R., Johnson, Charis L., Mehmood, Rashid, Swan, Patrick, Chu, Alphonse, Cregan, Sean P., Dilworth, F. Jeffrey, Howlett, Christopher J., Pin, Christopher L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576899/
https://ncbi.nlm.nih.gov/pubmed/28701342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-04-0254
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