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Probing the Binding Modes of a Multidomain Protein to Lipid-based Nanoparticles by Relaxation-based NMR

The interactions of two model multidomain proteins—covalently linked diubiquitins, Ub(2)—with lipid-based nanoparticles have been quantitatively probed by the measurements of NMR lifetime line broadening, ΔR(2). By combined analysis of ΔR(2) profiles arising from interactions with liposomes of varyi...

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Bibliographic Details
Published in:J Phys Chem Lett
Main Authors: Ceccon, Alberto, Tugarinov, Vitali, Boughton, Andrew J., Fushman, David, Clore, G. Marius
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576874/
https://ncbi.nlm.nih.gov/pubmed/28530812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpclett.7b01019
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