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Stress-inducible gene Atf3 in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis

Chemotherapy is a double-edged sword. It is anticancer because of its cytotoxicity. Paradoxically, by increasing chemoresistance and cancer metastasis, it is also procancer. However, the underlying mechanisms for chemotherapy-induced procancer activities are not well understood. Here we describe the...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Chang, Yi Seok, Jalgaonkar, Swati P., Middleton, Justin D., Hai, Tsonwin
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576783/
https://ncbi.nlm.nih.gov/pubmed/28784776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700455114
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