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Efficient and accurate causal inference with hidden confounders from genome-transcriptome variation data

Mapping gene expression as a quantitative trait using whole genome-sequencing and transcriptome analysis allows to discover the functional consequences of genetic variation. We developed a novel method and ultra-fast software Findr for higly accurate causal inference between gene expression traits u...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Wang, Lingfei, Michoel, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576763/
https://ncbi.nlm.nih.gov/pubmed/28821014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005703
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