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Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans
Sirtuins are NAD⁺-dependent deacetylases, lipoamidases, and ADP-ribosyltransferases that link cellular metabolism to multiple intracellular pathways that influence processes as diverse as cell survival, longevity, and cancer growth. Sirtuins influence the extent of neuronal death in stroke. However,...
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| Gepubliceerd in: | PLoS Genet |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576752/ https://ncbi.nlm.nih.gov/pubmed/28820880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006965 |
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