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Determination of disease phenotypes and pathogenic variants from exome sequence data in the CAGI 4 gene panel challenge

The use of gene panel sequence for diagnostic and prognostic testing is now widespread, but there are so far few objective tests of methods to interpret these data. We describe the design and implementation of a gene panel sequencing data analysis pipeline (VarP) and its assessment in a CAGI4 commun...

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Библиографические подробности
Опубликовано в: :Hum Mutat
Главные авторы: Kundu, Kunal, Pal, Lipika R., Yin, Yizhou, Moult, John
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576720/
https://ncbi.nlm.nih.gov/pubmed/28497567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23249
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