Antiparkinsonian effects of the "Radiprodil and Tozadenant" combination in MPTP-treated marmosets

OBJECTIVE: Investigate a combination of two clinically tested drugs, the NR2B antagonist Radiprodil and the A(2A) antagonist Tozadenant in the MPTP-treated marmoset model of Parkinson’s Disease (PD). BACKGROUND: In PD, there remains a need for the development of non-dopaminergic drugs to effectively...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Michel, Anne, Nicolas, Jean-Marie, Rose, Sarah, Jackson, Michael, Colman, Peter, Briône, Willy, Sciberras, David, Muglia, Pierandrea, Scheller, Dieter K., Citron, Martin, Downey, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576667/
https://ncbi.nlm.nih.gov/pubmed/28854243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182887
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