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Molecular targeting in acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogenous disease associated with distinct genetic and molecular abnormalities. Somatic mutations result in dysregulation of intracellular signaling pathways, epigenetics, and apoptosis of the leukemia cells. Understanding the basis for the dysregulated processes...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Lim, Seah H., Dubielecka, Patrycja M., Raghunathan, Vikram M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576374/
https://ncbi.nlm.nih.gov/pubmed/28851395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1281-x
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