Design and rationale of the Procalcitonin Antibiotic Consensus Trial (ProACT), a multicenter randomized trial of procalcitonin antibiotic guidance in lower respiratory tract infection

BACKGROUND: Overuse of antibiotics is a major public health problem, contributing to growing antibiotic resistance. Procalcitonin has been reported to be commonly elevated in bacterial, but not viral infection. Multiple European trials found procalcitonin-guided care reduced antibiotic use in lower...

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Udgivet i:BMC Emerg Med
Main Authors: Huang, David T., Angus, Derek C., Chang, Chung-Chou H., Doi, Yohei, Fine, Michael J., Kellum, John A., Peck-Palmer, Octavia M., Pike, Francis, Weissfeld, Lisa A., Yabes, Jonathan, Yealy, Donald M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Study Protocol
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576372/
https://ncbi.nlm.nih.gov/pubmed/28851296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12873-017-0138-1
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