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High-Content Assay Multiplexing for Vascular Toxicity Screening in Induced Pluripotent Stem Cell-Derived Endothelial Cells and Human Umbilical Vein Endothelial Cells

Endothelial cells (ECs) play a major role in blood vessel formation and function. While there is longstanding evidence for the potential of chemical exposures to adversely affect EC function and vascular development, the hazard potential of chemicals with respect to vascular effects is not routinely...

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Bibliographic Details
Published in:Assay Drug Dev Technol
Main Authors: Iwata, Yasuhiro, Klaren, William D., Lebakken, Connie S., Grimm, Fabian A., Rusyn, Ivan
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576216/
https://ncbi.nlm.nih.gov/pubmed/28771372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2017.786
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