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Non-Alcoholic Fatty Liver Disease (NAFLD) - Pathogenesis, Classification, and Effect on Drug Metabolizing Enzymes and Transporters

Non-alcoholic fatty liver disease (NAFLD) is a spectrum of liver disorders. It is defined by the presence of steatosis in more than 5 % of hepatocytes with little or no alcohol consumption. Insulin resistance, the metabolic syndrome or type 2 diabetes and genetic variants of PNPLA3 or TM6SF2 seem to...

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Dettagli Bibliografici
Pubblicato in:Drug Metab Rev
Autori principali: Cobbina, Enoch, Akhlaghi, Fatemeh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576152/
https://ncbi.nlm.nih.gov/pubmed/28303724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/03602532.2017.1293683
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