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Dual-targeted anti-TB/anti-HIV heterodimers

HIV and M. tuberculosis are two intersecting epidemics making the search for new dual action drugs against both pathogens extremely important. Here, we report on the synthesis and suppressive activities of five dual-targeted HIV/TB compounds. These compounds constitute heterodimers of AZT, as anti-H...

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Dettagli Bibliografici
Pubblicato in:Antiviral Res
Autori principali: Alexandrova, Liudmila, Zicari, Sonia, Matyugina, Elena, Khandazhinskaya, Anastasia, Smirnova, Tatiana, Andreevskaya, Sofia, Chernousova, Larisa, Vanpouille, Christophe, Kochetkov, Sergei, Margolis, Leonid
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576140/
https://ncbi.nlm.nih.gov/pubmed/28743447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.07.011
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