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Carbon Monoxide Preserves Circadian Rhythm to Reduce the Severity of Subarachnoid Hemorrhage in Mice

BACKGROUND AND PURPOSE: Subarachnoid hemorrhage (SAH) is associated with a temporal pattern of stroke incidence. We hypothesized that natural oscillations in gene expression controlling circadian rhythm impact the severity of neuronal injury. We moreover predict that heme oxygenase-1 (HO-1/Hmox1) an...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Schallner, Nils, Lieberum, Judith-Lisa, Gallo, David, LeBlanc, Robert H., Fuller, Patrick M., Hanafy, Khalid A., Otterbein, Leo E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575974/
https://ncbi.nlm.nih.gov/pubmed/28747460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.016165
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