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NMR structure of the C-terminal transmembrane domain of the HDL receptor, SR-BI, and a functionally-relevant leucine zipper motif
The interaction of high density lipoprotein (HDL) with its receptor, scavenger receptor BI (SR-BI), is critical for lowering plasma cholesterol levels and reducing the risk for cardiovascular disease. The HDL/SR-BI complex facilitates delivery of cholesterol into cells and is likely mediated by rece...
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| Veröffentlicht in: | Structure |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5575897/ https://ncbi.nlm.nih.gov/pubmed/28162952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.01.001 |
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