Linoleic acid metabolite leads to steroid resistant asthma features partially through NF-κB

Studies have highlighted the role of nutritional and metabolic modulators in asthma pathobiology. Steroid resistance is an important clinical problem in asthma but lacks good experimental models. Linoleic acid, a polyunsaturated fatty acid, has been linked to asthma and glucocorticoid sensitivity. I...

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Udgivet i:Sci Rep
Main Authors: Panda, Lipsa, Gheware, Atish, Rehman, Rakhshinda, Yadav, Manish K., Jayaraj, B. S., Madhunapantula, SubbaRao V., Mahesh, Padukudru Anand, Ghosh, Balaram, Agrawal, Anurag, Mabalirajan, Ulaganathan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575291/
https://ncbi.nlm.nih.gov/pubmed/28851976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09869-9
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