Generation of a new infectious recombinant prion: a model to understand Gerstmann–Sträussler–Scheinker syndrome

Human transmissible spongiform encephalopathies (TSEs) or prion diseases are a group of fatal neurodegenerative disorders that include Kuru, Creutzfeldt-Jakob disease, Gerstmann-Sträussler-Scheinker syndrome (GSS), and fatal familial insomnia. GSS is a genetically determined TSE caused by a range of...

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Udgivet i:Sci Rep
Main Authors: Elezgarai, Saioa R., Fernández-Borges, Natalia, Eraña, Hasier, Sevillano, Alejandro M., Charco, Jorge M., Harrathi, Chafik, Saá, Paula, Gil, David, Kong, Qingzhong, Requena, Jesús R., Andréoletti, Olivier, Castilla, Joaquín
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575253/
https://ncbi.nlm.nih.gov/pubmed/28851967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09489-3
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