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Interleukin-21 gene polymorphism rs2221903 is associated with disease activity in patients with rheumatoid arthritis

INTRODUCTION: Interleukin-21 (IL-21) is a cytokine which plays a significant role in the pathogenesis and disease activity of rheumatoid arthritis (RA). Genetic polymorphisms in the IL-21 gene may alter the synthesis of IL-21. The aim of this study was to examine IL-21 and IL-21R polymorphisms in pa...

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Bibliographische Detailangaben
Veröffentlicht in:Arch Med Sci
Hauptverfasser: Malinowski, Damian, Paradowska-Gorycka, Agnieszka, Safranow, Krzysztof, Pawlik, Andrzej
Format: Artigo
Sprache:Inglês
Veröffentlicht: Termedia Publishing House 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575225/
https://ncbi.nlm.nih.gov/pubmed/28883856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2017.68945
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