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Reaction of cis-diamminedichloroplatinum (II) and DNA in B or Z conformation.

The nature of the adducts and the conformational changes produced in poly(dG-m5dC).poly(dG-m5dC) by cis-diamminedichloroplatinum(II) (cisPt) have been studied. In the reaction of cisPt and B-DNA, the main adduct is bidentate and arises from an intrastrand cross-link between two guanine residues sepa...

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Autors principals: Malinge, J M, Leng, M
Format: Artigo
Idioma:Inglês
Publicat: 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC557508/
https://ncbi.nlm.nih.gov/pubmed/6540171
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